The Church of St. Panteleimon was built from 1840 to 1847 by the famous Macedonian church builder Andrey Damyanov (1813-1878) together with his brothers. The bell tower was erected later in 1849. Near the church is the tomb of the Macedonian revolutionary Mile Popyordanov (1877-1901).
The Church of St. Nicholas was built in its present form on the ruins of an older temple dating from 1341. It was consecrated in 1867. The interior is decorated with frescoes and carved wooden elements. Most of the icons on display inside date from the 19th century, but some were also painted in the 17th and 18th centuries, mainly by local artists.
St. George's Monastery was built in 1860 on the site where an old monastery was destroyed by the Ottomans in the 14th century. The new church was built thanks to the contributions of the citizens of Negotino between 1860 and 1866. The monastery houses were built a little later than the construction of the monastery church in the 1870s.
The monastery of Treskavets was built from the 13th to the 14th. It was destroyed and rebuilt by the Serbian ruler Stefan Uroš II Milutin (1282-1321), and he is registered as "Ktetor" (founder) in the monastery. Partially abandoned in the 15th century, it has been restored several times since then. The monastery was seriously damaged by a fire in 2013.
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