St. Dominic's Basilica

The Cathedral of Perugia was built between 1345 and 1490, but it is not the first cathedral built in the city. Perugia, which has been an episcopal see since at least the 3rd century, has had several cathedrals whose location was gradually fixed around the year 1000. In 1569 the new cathedral was officially consecrated and in the 17th century, the brick structure was raised as can be seen today on the outer walls. The interior of the cathedral is rich in works of art from the Umbrian Renaissance.

The Basilica of San Pietro was built around 996 as an abbey church. In 1398 the abbey was burnt down by the inhabitants of Perugia, who accused Abbot Francesco Guidalotti of conspiracy. In 1591 a thirty-year reconstruction campaign began, led by Valentino Martell, which gave the complex its present style. The abbey was temporarily abolished by the French in 1799, and definitively abolished in 1890 to make way for an "Institute of Agricultural Education", today the Department of Agricultural, Food and Environmental Sciences of the University of Perugia.

The Basilica of St. Francis of Assisi is divided into two parts: one is known as the "lower church", built in the rock on one side of Mount Subiaso between 1228 and 1230, and the other as the "upper church", built above it between 1230 and 1253, in the Gothic style. The bell tower is in Romanesque style. The two churches, united under the same name of "basilica", have been listed as UNESCO World Heritage Sites since 2000. The body of St. Francis was secretly transferred to the crypt in 1230 and was so well hidden that it was only rediscovered in 1818.