Basilica of San Pietro

St. Dominic's Basilica was built at the beginning of the 14th century on the initiative of the Dominicans, according to a project by Giovanni Pisano (1248-1318). The work was completed in 1458. Between 1629 and 1632, the interior was completely refurbished by Carlo Maderno according to a Latin cross plan with three long naves in a sober style, all in white. All that remains of the original building is the cloister (1455-1579) and, at the level of the choir, a large Gothic window dating back to the 15th century. The two adjoining cloisters of the convent house the State Archives and the National Archaeological Museum of Umbria.

The Cathedral of Perugia was built between 1345 and 1490, but it is not the first cathedral built in the city. Perugia, which has been an episcopal see since at least the 3rd century, has had several cathedrals whose location was gradually fixed around the year 1000. In 1569 the new cathedral was officially consecrated and in the 17th century, the brick structure was raised as can be seen today on the outer walls. The interior of the cathedral is rich in works of art from the Umbrian Renaissance.

The Basilica of St. Francis of Assisi is divided into two parts: one is known as the "lower church", built in the rock on one side of Mount Subiaso between 1228 and 1230, and the other as the "upper church", built above it between 1230 and 1253, in the Gothic style. The bell tower is in Romanesque style. The two churches, united under the same name of "basilica", have been listed as UNESCO World Heritage Sites since 2000. The body of St. Francis was secretly transferred to the crypt in 1230 and was so well hidden that it was only rediscovered in 1818.