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The first mention of the church of Sant'Antonio Abate dates back to the early 14th century. Towards the end of the 14th century, the complex therefore already included the church, the hospital and the convent, and was managed by the hospitable monks of Antonia, who prepared the sacred dye used to treat the shingles. The first remodelling dates back to 1370, the next to the 17th century, which erased part of the original structure. On the orders of Cardinal Antonino Sersale, the structure was remodelled in 1779.

The church of Sant'Antonio abate was built in 1345 by the Compagnia di Sant'Antonio abate and, founded with the aim of giving shelter and hospitality to the sick and pilgrims, it was annexed to an Oratory and a Hospital. The architectural features of the 14th century have been preserved in the façade, in the ogival portal of Umbrian ambitus which contains a bas-relief dating from 1350. The interior, decorated with 18th-century stucco, contains altars and paintings of the 17th century.

The church of Sant'Antonio Abate was originally a Gothic building dating from the 14th century, erected by Friar Ciotto degli Abbati. After the patriarch moved from the castle of Udine to the new palace, it became the patriarchal chapel. The façade was completed between 1731 and 1734 and in 1733 by Giorgio Massari, commissioned by Dionisio Dolfin. Now deconsecrated, the church is used as an auditorium and hosts exhibitions.

The church of Sant'Antonio, formerly the convent of San Francesco, was built in the 13th century. In 1309 the bell tower was built by Master Antonio di Florio and a little later, in 1327, the church was completed and enlarged. The side of the church, punctuated by buttresses, has two windows, a rose window and a closed entrance; of the small arches that formed the crowning cornice, demolished during the Baroque reconstruction, a section remains near the bell tower.

The church of Sant'Elena was built in the 15th century where a monastery church had been built in the 12th century. At the beginning of the 15th century, as the monastery was without monks and with only the prior, Pope Gregory XII handed it over to the Order of Mount Olivet, who began a reconstruction that started in 1439. The new temple was consecrated in 1515. Recently, the church has been restored and re-consecrated and is open for worship.

The church of Sant'Elia was built from 1694 after an earlier church was damaged by the Val di Noto earthquake of 1693. The cycle of frescoes culminating in the painting on the nave vault of St. Elijah on the Chariot of Fire and Elisha, painted in 1706 by Antonio Filocamo, was damaged in the southern Calabrian earthquake of 1783. However, the vault and the painting were restored during reconstruction and restoration campaigns. In the Messina earthquake of 1908, the church suffered limited damage consisting of the collapse of the ceiling near the top of the façade.

The church of Sant'Eligio dei Ferrari was built in 1513 by the University of Ferrari on the site of the former church of San Giacomo d'Altopascio and San Martino di Monte Tito, both of which were granted to the University of Ferrari in 1453. The interior of the church, with a single nave and three altars on each side, is richly decorated with wood and golden stucco (1604).

The church of Sant'Erasmo was built in the 14th century and restored in 1490, and was attached to the hospice of the same name, probably founded by Bonvesin de la Riva in the 13th century and demolished in 1925. In the Middle Ages, pilgrims travelling along one of the Roman roads to Milan stopped at the Sant'Erasmo hospice in Legnano.

The church of St. Eusebius was dedicated in 1238 to the 4th-century martyr Eusebius of Rome. A church was already located here, probably since the 4th century. Under Pope Sixtus V (1585-1590), one of the first printing works in Rome was established in the Celestine monastery attached to the church. In 1627, the place of worship was raised from a priory to an abbey, which was abolished two centuries later in 1810. Numerous modifications and restorations were made to the church in the 17th, 18th and 20th centuries, but the original Romanesque style has been preserved.

The church of Sant'Isidoro a Capo le Case, part of a Franciscan complex, is one of the two Irish national churches. The church and monastery were built between 1622 and 1672, when Spanish Franciscan descalceati (Discalced) arrived to found a convent for their countrymen and built the church which they dedicated to the new Spanish saint. A few years later, the church and convent came under the authority of Irish Franciscan monks, fleeing their country under the persecution of the English Protestants.